Pharmacology Population Assignment Example | Topics and Well Written Essays - 1000 words

Pharmacology Population - Assignment ExampleIn a study by Bartelink, Rademaker, Schobben, et al. (2006), cosmos pk was found to be a very important approach through which not just pharmacokinetic information is obtained from thin data sets but also pharmacodynamic information obtained from this same sparse data set. Leeder (2004) also observed that there stages in the drug development process where the very massive community may be needed but with only a few observations per patient so as to determine the exact and unique differences with drug behavior in each patient found on special characteristics. To achieve this, population pk is employed or used to obtain information at both the phase II and phase III clinical trials among patients. It is not surprising that Ernest, Elder, Martini, et al. (2007) identified population pk as a practice associated with several pharmaceutical companies in the course of their drug development process. Certainly, population pk comes as a single most reliable mechanism by which dosage determination to drugs derriere be done due to the size of the population used in the sparse data sets, each of whom is observed for very specific outcomes based on their demographic and pathophysiology characteristics.Also writing on the ploughshare of population pk to drug development, Roosmarijn et al. (2011) found that there are instances when intensive blood have can be attained. Meanwhile, Hsieh and Korfmacher (2006) noted that where intensive blood sampling is possible, there is the benefit of replicating the outcomes with particular blood samples for a large population size. This means that where intensive blood sampling is not possible an alternative is needed to agree that almost all populations are catered for. Typical situations in drug development where intensive blood sampling has not been attainable include drug development processes for children, cancer, and AIDS.